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Published on April 27, 2010
ACCESS
PHARMACEUTICALS, INC.
2600
Stemmons Frwy, Suite 176
Dallas,
TX 75207
April 27,
2010
Via EDGAR and
Facsimile
United
States Securities and Exchange Commission
Division
of Corporate Finance
100 F
Street, NE
Washington,
D.C. 20549
Attention:
Bryan Pitko
Re: Access
Pharmaceuticals, Inc.
Post-effective Amendment No. 2 to
Registration Statement on Form S-1
File No. 333-149633
Ladies
and Gentlemen:
Pursuant to Rule 461 of the Securities
Act of 1933, as amended, and Rule 12(b)-6 of the Securities Exchange Act of
1934, as amended, Access Pharmaceuticals, Inc., a Delaware corporation (the
“Company”), hereby requests that the effectiveness of the Company’s
above-referenced Post-effective Amendment No. 2 to Registration Statement on
Form S-1, be accelerated to 4
p.m. Eastern Time on Thursday, April 29, 2010, or as soon as practicable
before or thereafter, unless you are orally or in writing notified to the
contrary by the Company prior to such date and time.
The Company hereby acknowledges
that:
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should
the Securities and Exchange Commission (the “Commission”) or the staff of
the Commission (the “Staff”), acting pursuant to delegated authority,
declare the filing effective, it does not foreclose the Commission from
taking any action with respect to the
filing;
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the
action of the Commission or the Staff, acting pursuant to delegated
authority, in declaring the filing effective, does not relieve the Company
from its full responsibility for the adequacy and accuracy of the
disclosure in the filing; and
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the
Company may not assert Staff comments and the declaration of effectiveness
as a defense in any proceeding initiated by the Commission or any person
under the federal securities laws of the United
States.
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Should you have any questions regarding
this request, please do not hesitate to contact John J. Concannon (617-951-8874)
of Bingham McCutchen LLP.
Sincerely,
ACCESS
PHARMACEUTICALS, INC.
/s/ Stephen B.
Thompson
Stephen
B. Thompson
Chief
Financial Officer
cc: John
J. Concannon, Bingham
McCutchen LLP