Form: EFFECT

Notice of Effectiveness

December 12, 2022

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

Notice of Effectiveness

Effectiveness Date: December 12, 2022 4:00 P.M.
Form: S-3
CIK: 0000318306
Company Name: ABEONA THERAPEUTICS INC.
File Number: 333-268619