FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
FEINBERG LARRY N
  2. Issuer Name and Ticker or Trading Symbol
ACCESS PHARMACEUTICALS INC [ACCP]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
C/O ORACLE ASSOCIATES, LLC, 200 GREENWICH AVENUE, 3RD FLOOR
3. Date of Earliest Transaction (Month/Day/Year)
02/01/2005
(Street)

GREENWICH, CT 06830
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock, par value $0.01 per share ("Common Stock") 02/01/2005   P   30,200 A $ 2.69 1,242,500 (2) (3) I See footnote (1)
Common Stock 02/01/2005   S   30,200 D $ 2.69 1,242,500 (2) (3) I See footnote (1)
Common Stock 12/31/2005   P   15,636 A $ 0.65 1,718,121 (2) (3) I See footnote (1)
Common Stock 12/31/2005   P   82,745 A $ 0.65 1,718,121 (2) (3) I See footnote (1)
Common Stock 12/31/2005   P   299,056 A $ 0.65 1,718,121 (2) (3) I See footnote (1)
Common Stock 12/31/2005   P   78,184 A $ 0.65 1,718,121 (2) (3) I See footnote (1)
Common Stock 06/05/2006   J   1,374,497 D (4) 343,624 (2) (3) I See footnote (1)
Common Stock 09/01/2006   S   0.80 D (5) 343,623 (2) (3) I See footnote (1)
Common Stock 09/01/2006   S   0.20 D (5) 343,623 (2) (3) I See footnote (1)
Common Stock 09/01/2006   S   0.20 D (5) 343,623 (2) (3) I See footnote (1)
Common Stock 01/22/2007   S   6,040 D $ 2.53 343,623 (2) (3) I See footnote (1)
Common Stock 01/22/2007   P   6,040 A $ 2.53 343,623 (2) (3) I See footnote (1)
Common Stock 02/26/2007   S   19,000 D $ 7.314 318,623 (2) (3) I See footnote (1)
Common Stock 02/26/2007   S   5,000 D $ 7.314 318,623 (2) (3) I See footnote (1)
Common Stock 02/26/2007   S   1,000 D $ 7.314 318,623 (2) (3) I See footnote (1)
Common Stock 02/27/2007   S   300 D $ 7 318,223 (2) (3) I See footnote (1)
Common Stock 02/27/2007   S   100 D $ 7 318,223 (2) (3) I See footnote (1)
Common Stock 02/28/2007   S   10,000 D $ 7.10 302,523 (2) (3) I See footnote (1)
Common Stock 02/28/2007   S   4,500 D $ 7.10 302,523 (2) (3) I See footnote (1)
Common Stock 03/01/2007   S   1,200 D $ 7.125 302,523 (2) (3) I See footnote (1)
Common Stock 06/19/2007   S   40,000 D $ 5.17 302,523 (2) (3) I See footnote (1)
Common Stock 06/19/2007   S   20,000 D $ 5.17 302,523 (2) (3) I See footnote (1)
Common Stock 06/19/2007   P   60,000 A $ 5.17 302,523 (2) (3) I See footnote (1)
Common Stock 07/23/2007   S   4,000 D $ 4.3563 298,523 (2) (3) I See footnote (1)
Common Stock 07/24/2007   S   2,040 D $ 4.35 296,483 (2) (3) I See footnote (1)
Common Stock 02/12/2008   P   29,736 A $ 3.15 296,483 (2) (3) I See footnote (1)
Common Stock 02/12/2008   S   29,736 D $ 3.15 296,483 (2) (3) I See footnote (1)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Series A Cumulative Convertible Preferred Stock (6) 11/10/2007   J(7)   437     (6)   (6) Common Stock 1,457,707 (7) 437 I See footnote (1)
Common Stock Purchase Warrants (9) 11/10/2007   J(7)   728,850     (9)   (9) Common Stock 728,850 (7) 728,850 I See footnote (1)
Series A Cumulative Convertible Preferred Stock (6) 03/11/2008   P   72     (6)   (6) Common Stock 240,000 (8) 72 I See footnote (1)
Series A Cumulative Convertible Preferred Stock (6) 03/11/2008   S   72     (6)   (6) Common Stock 240,000 (8) 72 I See footnote (1)
Common Stock Purchase Warrants (9) 03/11/2008   P   119,811     (9)   (9) Common Stock 119,811 (8) 119,811 I See footnote (1)
Common Stock Purchase Warrants (9) 03/11/2008   S   119,811     (9)   (9) Common Stock 119,811 (8) 119,811 I See footnote (1)

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
FEINBERG LARRY N
C/O ORACLE ASSOCIATES, LLC
200 GREENWICH AVENUE, 3RD FLOOR
GREENWICH, CT 06830
    X    
Oracle Associates LLC
200 GREENWICH AVENUE, 3RD FLOOR
GREENWICH, CT 06830
    X    
ORACLE PARTNERS LP
C/O ORACLE ASSOCIATES, LLC
200 GREENWICH AVENUE, 3RD FLOOR
GREENWICH, CT 06830
    X    
ORACLE INSTITUTIONAL PARTNERS L P
C/O ORACLE ASSOCIATES, LLC
200 GREENWICH AVENUE, 3RD FLOOR
GREENWICH, CT 06830
    X    
ORACLE INVESTMENT MANAGEMENT INC
200 GREENWICH AVE, 3RD FLOOR
GREENWICH, CT 06830
    X    

Signatures

 /s/ Larry N. Feinberg   06/10/2008
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) See Exhibit 99.1.
(2) See Exhibit 99.1.
(3) See Exhibit 99.1.
(4) See Exhibit 99.1.
(5) See Exhibit 99.1.
(6) See Exhibit 99.1.
(7) See Exhibit 99.1.
(8) See Exhibit 99.1.
(9) See Exhibit 99.1.
 
Remarks:
(10) - (15) See Exhibit 99.1.

Exhibit List:

Exhibit 99.1 - Explanation of Responses
Exhibit 99.2 - Joint Filer Information for Oracle Associates
Exhibit 99.3 - Joint Filer Information for Oracle Partners
Exhibit 99.4 - Joint Filer Information for Oracle Institutional Partners
Exhibit 99.5 - Joint Filer Information for Oracle Investment Management

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

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