Quarterly report pursuant to Section 13 or 15(d)

STOCK-BASED COMPENSATION - Stock-Based Option Compensation (Details)

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STOCK-BASED COMPENSATION - Stock-Based Option Compensation (Details) - USD ($)
 3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Stock-based compensation expense included in operating expense        
Stock-based compensation expense included in operating expense     $ 3,781,000 $ 4,573,000
Total stock-based compensation expense     3,781,000 4,573,000
Stock Options        
Stock-based compensation expense included in operating expense        
Stock-based compensation expense included in operating expense $ 1,678,000 $ 2,673,000 3,781,000 4,573,000
Total stock-based compensation expense 1,678,000 2,673,000 3,781,000 4,573,000
Tax benefit 0 0 0 0
Stock-based compensation expense, net of tax 1,678,000 2,673,000 3,781,000 4,573,000
Stock Options | Research and Development        
Stock-based compensation expense included in operating expense        
Stock-based compensation expense included in operating expense 1,009,000 900,000 2,041,000 1,744,000
Total stock-based compensation expense 1,009,000 900,000 2,041,000 1,744,000
Stock Options | General and Administrative        
Stock-based compensation expense included in operating expense        
Stock-based compensation expense included in operating expense 669,000 1,773,000 1,740,000 2,829,000
Total stock-based compensation expense 669,000 1,773,000 1,740,000 2,829,000
Restricted Stock        
Stock-based compensation expense included in operating expense        
Stock-based compensation expense included in operating expense 78,000 172,000 250,000 344,000
Total stock-based compensation expense 78,000 172,000 250,000 344,000
Tax benefit 0 0 0 0
Stock-based compensation expense, net of tax 78,000 172,000 250,000 344,000
Restricted Stock | Research and Development        
Stock-based compensation expense included in operating expense        
Stock-based compensation expense included in operating expense 0 0 0 0
Total stock-based compensation expense 0 0 0 0
Restricted Stock | General and Administrative        
Stock-based compensation expense included in operating expense        
Stock-based compensation expense included in operating expense 78,000 172,000 250,000 344,000
Total stock-based compensation expense $ 78,000 $ 172,000 $ 250,000 $ 344,000