Annual report pursuant to Section 13 and 15(d)

Consolidated Statements of Stockholders' Equity

v3.21.1
Consolidated Statements of Stockholders' Equity - USD ($)
Common Stock [Member]
Additional Paid-in Capital [Member]
Retained Earnings [Member]
AOCI Attributable to Parent [Member]
Total
Beginning balance, value at Dec. 31, 2018 $ 479,000 $ 543,754,000 $ (410,188,000) $ 134,045,000
Beginning balance, shares at Dec. 31, 2018 47,944,486        
Stock option-based compensation expense 7,338,000 7,338,000
Restricted stock-based compensation expense 899,000 899,000
Issuance of common stock and pre-funded warrants  in connection with public offering, net of offering costs $ 324,000 95,648,000 95,972,000
Issuance of common stock and pre-funded warrants in connection with public offering, net of offering costs, shares 32,382,945        
Issuance of common stock under open market sale agreement $ 31,000 16,930,000 16,961,000
Issuance of common stock under open market sale agreement, shares 3,086,950        
Issuance of common stock in connection with the exercise of stock options $ 3,000 966,000 969,000
Issuance of common stock in connection with the exercise of stock options, shares 303,129        
Issuance of common stock in connection  with restricted share awards, net of cancellations $ 4,000 (4,000)
Issuance of common stock in connection with restricted share awards, net of cancellations, shares 354,625        
Shares returned in connection with arbitration  ruling on licensing agreement $ (5,000) (1,467,000) (1,472,000)
Shares returned in connection with arbitration ruling on licensing agreement, shares (450,000)        
Other comprehensive loss        
Net loss (76,282,000) (76,282,000)
Ending balance, value at Dec. 31, 2019 $ 836,000 664,064,000 (486,470,000) 178,430,000
Ending balance, shares at Dec. 31, 2019 83,622,135        
Stock option-based compensation expense 5,853,000 5,853,000
Restricted stock-based compensation expense 2,334,000 2,334,000
Issuance of common stock in connection with the exercise of stock options $ 1,000 176,000 177,000
Issuance of common stock in connection with the exercise of stock options, shares 77,560        
Issuance of common stock in connection  with restricted share awards, net of cancellations $ 34,000 (34,000)
Issuance of common stock in connection with restricted share awards, net of cancellations, shares 3,414,928        
Issuance of common stock in connection with the  exercise of pre-funded warrants $ 90,000 (89,000) 1,000
Issuance of common stock in connection with the exercise of pre-funded warrants, shares 9,017,055        
Other comprehensive loss (10,000) (10,000)
Net loss (84,234,000) (84,234,000)
Ending balance, value at Dec. 31, 2020 $ 961,000 $ 672,304,000 $ (570,704,000) $ (10,000) $ 102,551,000
Ending balance, shares at Dec. 31, 2020 96,131,678