Annual report pursuant to Section 13 and 15(d)

Nature of Operations and Summary of Significant Accounting Policies (Details Narrative)

v3.20.1
Nature of Operations and Summary of Significant Accounting Policies (Details Narrative) - USD ($)
 12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Jan. 02, 2019
Jan. 02, 2018
Oct. 16, 2017
Dec. 31, 2016
Cash, cash equivalents and short-term investments $ 129,258,000            
Net assets 178,430,000            
Net cash used in operating activities (62,820,000) $ (39,111,000) $ (22,655,000)        
Allowance for doubtful accounts receivable          
Receivables 81,000          
Right-of-use lease assets 8,047,000          
Operating lease liability 7,950,000            
Goodwill 32,466,000 32,466,000          
Goodwill impairment        
Stockholders' equity 178,430,000 134,045,000 170,098,000   $ 6,300,000   $ 99,098,000
Deferred revenue 296,000 296,000 2,600,000   2,600,000    
Accumulated deficit (486,470,000) (410,188,000)     2,600,000    
Grants Receivable 5,700,000 5,700,000          
Aggregate amount to the performance obligations 300,000 300,000          
Accounting Standards Update 2016-02 [Member]              
Right-of-use lease assets       $ 8,900,000      
Operating lease liability       $ 8,900,000      
MPS IIIA [Member]              
Value in installments for the advancement           $ 13,900,000  
MPS IIIB [Member]              
Value in installments for the advancement           $ 13,900,000  
Foundation Revenues [Member]              
Deferred revenue $ 0 $ 2,800,000          
Licenses [Member]              
Deferred revenue     $ 3,700,000   3,700,000    
Accumulated deficit         $ 3,700,000