Quarterly Financial Data (Unaudited) - Schedule of Quarterly Financial Information (Details) - USD ($) |
3 Months Ended | 12 Months Ended | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Dec. 31, 2019 |
Sep. 30, 2019 |
Jun. 30, 2019 |
Mar. 31, 2019 |
Dec. 31, 2018 |
Sep. 30, 2018 |
Jun. 30, 2018 |
Mar. 31, 2018 |
Dec. 31, 2019 |
Dec. 31, 2018 |
Dec. 31, 2017 |
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| Revenues | $ 2,998,000 | $ 837,000 | |||||||||
| Research and development | $ 9,605,000 | $ 10,917,000 | $ 16,307,000 | $ 11,737,000 | $ 9,470,000 | $ 13,150,000 | $ 7,916,000 | $ 8,162,000 | 48,566,000 | 38,698,000 | 16,989,000 |
| General and administrative | 4,734,000 | 4,700,000 | 5,612,000 | 5,659,000 | 7,631,000 | 4,970,000 | 4,627,000 | 2,878,000 | 20,705,000 | 20,106,000 | 10,943,000 |
| Loss from operations | (16,411,000) | (17,649,000) | (23,976,000) | (19,054,000) | (18,010,000) | (16,916,000) | (12,557,000) | (10,683,000) | (77,090,000) | (58,166,000) | (27,836,000) |
| Net loss | $ (16,431,000) | $ (17,372,000) | $ (23,924,000) | $ (18,555,000) | $ (17,479,000) | $ (16,419,000) | $ (12,243,000) | $ (10,530,000) | $ (76,282,000) | $ (56,671,000) | $ (27,319,000) |
| Basic and diluted loss per common share | $ (0.30) | $ (0.35) | $ (0.49) | $ (0.39) | $ (0.36) | $ (0.34) | $ (0.26) | $ (0.22) | $ (1.51) | $ (1.19) | $ (0.66) |
| Weighted average number of common shares outstanding - basic and diluted | 54,718,776 | 49,721,753 | 48,961,988 | 47,948,421 | 47,944,486 | 47,794,394 | 47,303,518 | 47,060,523 | 50,354,596 | 47,528,248 | 41,636,752 |
| Foundation Revenues [Member] | |||||||||||
| Revenues | $ 369,000 | $ 1,687,000 | $ 259,000 | $ 481,000 | $ 2,796,000 | ||||||
| Royalties [Member] | |||||||||||
| Revenues | $ 113,000 | $ 22,000 | $ 17,000 | $ 50,000 | $ 202,000 | $ 235,000 | |||||
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- Definition The amount of net income or loss for the period per each share in instances when basic and diluted earnings per share are the same amount and reported as a single line item on the face of the financial statements. Basic earnings per share is the amount of net income or loss for the period per each share of common stock or unit outstanding during the reporting period. Diluted earnings per share includes the amount of net income or loss for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition The aggregate total of expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, which are not directly or indirectly associated with the manufacture, sale or creation of a product or product line. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition The net result for the period of deducting operating expenses from operating revenues. No definition available.
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- Definition The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Average number of shares or units issued and outstanding that are used in calculating basic and diluted earnings per share (EPS). No definition available.
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