Annual report pursuant to Section 13 and 15(d)

CONSOLIDATED STATEMENTS OF OPERATIONS

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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Revenues:      
Total revenues $ 2,998,000 $ 837,000 $ 889,000
Expenses:      
Research and development 38,698,000 16,989,000 10,655,000
General and administrative 20,106,000 10,943,000 13,290,000
Depreciation and amortization 2,360,000 741,000 825,000
Total expenses 61,164,000 28,673,000 24,770,000
Loss from operations (58,166,000) (27,836,000) (23,881,000)
Interest and miscellaneous income 1,506,000 525,000 2,014,000
Interest and other expense (11,000) (8,000) (6,000)
Net loss $ (56,671,000) $ (27,319,000) $ (21,873,000)
Basic and diluted loss per common share (in dollars per share) $ (1.19) $ (0.66) $ (0.64)
Weighted average number of common shares outstanding - basic and diluted (in shares) 47,528,248 41,636,752 34,180,253
Foundation revenues [Member]      
Revenues:      
Total revenues $ 2,796,000 $ 0 $ 0
License revenues [Member]      
Revenues:      
Total revenues 0 602,000 602,000
Royalties [Member]      
Revenues:      
Total revenues $ 202,000 $ 235,000 $ 287,000